Research Paper Advance Articles pp 24156—24167

Gut microbiota transplantation from db/db mice induces diabetes-like phenotypes and alterations in Hippo signaling in pseudo germ-free mice

Figure 4. Alterations in the metabolic parameters after fecal transplantation in pseudo germ-free mice. (A) Schedule of our study. Mice were treated orally with fecal microbiota from db/db or m/m mice for 14 consecutive days after receiving large doses of antibiotics for 2 weeks. Peripheral tissues were collected for subsequent experiments on day 29. (B) Blood glucose. (C) Body weight. (D) Food intake. (E) Water intake. Data are shown as mean ± SEM values (n = 7). *P < 0.05, **P < 0.01, or ***P < 0.001. CONT, control; GF, germ-free.