Research Paper Volume 12, Issue 24 pp 25469—25486

Tumor necrosis factor superfamily 14 is critical for the development of renal fibrosis

Figure 4. Increased renal tubular cell integrity in Tnfsf14-deficient mice after UUO. Kidney tissues of Tnfsf14+/+ and Tnfsf14−/− mice were collected after UUO surgery for 7 days. (A) E-cadherin expression in kidney tissues was measured by western blot. Representative western blot (Left) and quantitative data (Right) are presented. (B) E-cadherin expression in kidney tissues was measured by immunofluorescence. Sham group was used as the control of UUO. The data were representative of the results of three independent experiments. Values are represented as mean ± SEM. Original magnification ×400. n = 5 per group. ***P < 0.001.