Research Paper Advance Articles pp 24242—24254

TNFAIP3 ameliorates the degeneration of inflammatory human nucleus pulposus cells by inhibiting mTOR signaling and promoting autophagy

Figure 4. Knockdown of TNFAIP3 increases mTOR signaling in LPS-treated human NPCs. (A) The mTOR signaling was measured by Western blot in LPS-stimulated human NPCs at the phosphorylation level of mTOR at S2448. (B) Relative phosphorylation level of the mTOR. Data are represented by the mean ± standard deviation of 3 independent replicates. *** P<0.01, ** P<0.05, * P>0.05 by the Student’s t-test.