COVID-19 Research Perspective Volume 12, Issue 19 pp 18797—18803

Using the common cold virus as a naturally occurring vaccine to prevent COVID-19: Lessons from Edward Jenner

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Figure 2. Protein sequence alignments of the Viral Spike Glycoproteins (VSGs) from two related Human Coronaviruses, namely OC43 and HKU1. Note the high homology between OC43 and HKU1, with up to 78% similarity. Generated using the online program BLASTP, by pairwise sequence analysis. The same potentially shared epitopes, highlighted in color in Figure 1, are also highlighted here, for comparison.