Research Paper Volume 12, Issue 20 pp 20024—20046

GDF11 induces mild hepatic fibrosis independent of metabolic health

Figure 1. Correlation between GDF11 mRNA levels, clinico-pathologic characteristics and gene expression in morbidly obese patients (n=33). Correlations between GDF11 mRNA levels and (A) NAFLD or NASH, (B) Kleiner score (0-8) and (C) expression levels of Col1A1, SREBP1, PPARγ and CPT1 in the whole cohort of morbidly obese patients (n=33) and subgroups with NAFLD (n=20) or NASH (n=13). The Pearson correlation’s coefficient is shown.