Research Paper Volume 12, Issue 24 pp 25778—25804

Identification of prognostic aging-related genes associated with immunosuppression and inflammation in head and neck squamous cell carcinoma


Figure 6. Enriched pathways of the high-risk and low-risk groups via GSEA. (A) Multiple GSEA for metabolism of the high-risk group: galactose metabolism and nitrogen metabolism. (B) Multiple GSEA for cancer pathways of the high-risk group: the ERBB signaling pathway and pathway in cancer. (C) Multiple GSEA for metabolism of the low-risk group: arachidonic acid metabolism, fatty acid metabolism and linoleic acid metabolism. (D) Multiple GSEA for inflammation and immunity of the low-risk group: the B cell receptor signaling pathway, T cell receptor signaling pathway, intestinal immune network for IgA production and cytokine_cytokine receptor interaction. (E) Single GSEA showing the B cell receptor signaling pathway. (F) Single GSEA showing the T cell receptor signaling pathway.