Research Paper Volume 13, Issue 2 pp 2049—2072

Tumor-associated macrophage polarization promotes the progression of esophageal carcinoma

Correlation of FGL2, ERI1 and WNT5B levels with infiltrating immune cell levels in ESCA. FGL2 expression exhibited a significant negative correlation with ESCA tumor purity, and significant positive correlations with the infiltrating levels of B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils and DCs. ERI1 and WNT5B expression did not correlate significantly with ESCA tumor purity. ERI1 expression correlated weakly with the infiltrating levels of B cells, CD8+ T cells and DCs. WNT5B expression only correlated weakly with macrophage levels. P

Figure 4. Correlation of FGL2, ERI1 and WNT5B levels with infiltrating immune cell levels in ESCA. FGL2 expression exhibited a significant negative correlation with ESCA tumor purity, and significant positive correlations with the infiltrating levels of B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils and DCs. ERI1 and WNT5B expression did not correlate significantly with ESCA tumor purity. ERI1 expression correlated weakly with the infiltrating levels of B cells, CD8+ T cells and DCs. WNT5B expression only correlated weakly with macrophage levels. P < 0.05 was considered statistically significant.