Research Paper Volume 13, Issue 2 pp 2049—2072

Tumor-associated macrophage polarization promotes the progression of esophageal carcinoma

Analysis of DEGs between M1 and M2 macrophages. (A, B) Histogram of enriched GO terms (BP: Biological Process, MF: Molecular Function, CC: Cellular Component) (A) and bubble plot of enriched KEGG pathways (B). The rank criterion was an FDR C) PPI network constructed from 54 hub genes, with the red region representing the most closely connected module. A comprehensive Gt score > 0.7 was considered statistically significant. (D) Top 30 genes with the greatest degree of differential expression. The ordinate lists the gene name and the abscissa represents the degree of differential expression.

Figure 9. Analysis of DEGs between M1 and M2 macrophages. (A, B) Histogram of enriched GO terms (BP: Biological Process, MF: Molecular Function, CC: Cellular Component) (A) and bubble plot of enriched KEGG pathways (B). The rank criterion was an FDR < 0.05. The abscissa represents the percentage of DEGs enriched in each term or pathway; the size represents the number of DEGs enriched in each item or pathway; and the color represents the adjusted P-value. (C) PPI network constructed from 54 hub genes, with the red region representing the most closely connected module. A comprehensive Gt score > 0.7 was considered statistically significant. (D) Top 30 genes with the greatest degree of differential expression. The ordinate lists the gene name and the abscissa represents the degree of differential expression.