Research Paper Volume 12, Issue 22 pp 22495—22508

Cell differentiation and aging accompanied by depletion of the ACE2 protein

Figure 1. ACE2 in lung A549 cells and mouse embryonic heart sections. (A) 3D-projection of images obtained by confocal microscopy. The ACE2 protein (red fluorescence) was visualized by immunofluorescence. (B) ACE2 protein (green fluorescence) expression in A549 cells. (C) ACE2 expression in mouse heart section (red fluorescence) [see right atrium (RA), left atrium (LA), aorta (AO) and pulmonary trunk (PT), right ventriculus (RV), and left ventriculus (LV) or intraventricular septum (IVS)]. The blue ellipse shows the anatomical part associated with the aorta.