Research Paper Volume 12, Issue 22 pp 22495—22508

Cell differentiation and aging accompanied by depletion of the ACE2 protein

Figure 5. Level of the ACE2 protein studied in explanted embryonic hearts treated by HDAC inhibitors. (A) In nontreated, TSA (trichostatin A), and SAHA (suberoylanilide hydroxamic acid)-treated explanted mouse hearts at stage e15, the ACE2 protein level was analyzed. (B) Quantification of the protein levels, as assessed by western blotting, was performed using ImageJ software.