Research Paper Volume 12, Issue 22 pp 22495—22508

Cell differentiation and aging accompanied by depletion of the ACE2 protein

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Figure 5. Level of the ACE2 protein studied in explanted embryonic hearts treated by HDAC inhibitors. (A) In nontreated, TSA (trichostatin A), and SAHA (suberoylanilide hydroxamic acid)-treated explanted mouse hearts at stage e15, the ACE2 protein level was analyzed. (B) Quantification of the protein levels, as assessed by western blotting, was performed using ImageJ software.