Research Paper Volume 13, Issue 1 pp 1120—1131

Hsa_circ_0079480 promotes tumor progression in acute myeloid leukemia via miR-654-3p/HDGF axis

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Figure 7. MiR-654-3p inhibitor or HDGF overexpression rescued si-circ0079480-stimulated phenotypes in AML cells. (AD) MiR-654-3p inhibitor abolished the effects of si-circ0079480 on HDGF expression in AML cells. (EH) EdU and cell apoptosis assays indicated that miR-654-3p inhibitor (or HDGF overexpression) reversed the effects of si-circ0079480 on AML progression. (I) Schematic of hsa_circ_0079480/miR-654-3p/HDGF in AML. *P<0.05.