Research Paper Volume 13, Issue 2 pp 2251—2263

β-Arrestin-2 attenuates hepatic ischemia-reperfusion injury by activating PI3K/Akt signaling

ARRB2 protects against hepatic ischemia-reperfusion injury in mice. (A) Analysis of serum ALT and AST levels in Sham, WT + IR and KO + IR groups. (B) Representative H&E staining of liver tissues (original magnification, 100×). (C) Bar graphs show Suzuki score and necrosis area revealed by H&E staining. The data are presented as the Mean ± SD, n = 6. *P #P

Figure 1. ARRB2 protects against hepatic ischemia-reperfusion injury in mice. (A) Analysis of serum ALT and AST levels in Sham, WT + IR and KO + IR groups. (B) Representative H&E staining of liver tissues (original magnification, 100×). (C) Bar graphs show Suzuki score and necrosis area revealed by H&E staining. The data are presented as the Mean ± SD, n = 6. *P < 0.01, compared to Sham group, #P< 0.01, compared to WT + IR group by Student's-t test.