Research Paper Volume 13, Issue 2 pp 2264—2278

Silencing LINC00482 inhibits tumor-associated inflammation and angiogenesis through down-regulation of MMP-15 via FOXA1 in bladder cancer

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Figure 2.

LINC00482 is highly expressed in bladder cancer tissues and cells. (A) The comparison of LINC00482 expression between the bladder cancer and adjacent normal tissues detected by RT-qPCR, n = 84, * p < 0.05 vs. adjacent normal tissues; (B) the expression of LINC00482 in 4 human bladder cancer cell lines and human normal bladder epithelial cells (SV-HUC-1) detected by RT-qPCR, * p < 0.05 vs. SV-HUC-1 cells; (C) the localization of LINC00482 in different cells by online analysis; (D) subcellular localization of LINC00482 detected by RNA-FISH (× 400). The measurement data were presented as mean ± standard deviations. Paired t-test was used for intra-group comparison, while comparisons among multiple groups were analyzed by one-way analysis of variance, followed by Tukey’s post-hoc test. Experiments were repeated three times.