Research Paper Volume 13, Issue 2 pp 2310—2329

B3GNT3 overexpression promotes tumor progression and inhibits infiltration of CD8+ T cells in pancreatic cancer

Association between B3GNT3 expression and somatic mutations. (A) KRAS, TP53, CDKN2A, and SMAD4 mutation status were significantly associated with higher expression of B3GNT3. (B–D) Correlation analysis of KRAS, SMAD4, and B3GNT3. PC, pancreatic cancer; TCGA, the Cancer Genome Atlas; WT: wild type; MUT: mutation. (*P value

Figure 5. Association between B3GNT3 expression and somatic mutations. (A) KRAS, TP53, CDKN2A, and SMAD4 mutation status were significantly associated with higher expression of B3GNT3. (BD) Correlation analysis of KRAS, SMAD4, and B3GNT3. PC, pancreatic cancer; TCGA, the Cancer Genome Atlas; WT: wild type; MUT: mutation. (*P value < 0.05; **P value < 0.01;***P value < 0.001; ****P value < 0.0001).