Research Paper Volume 13, Issue 2 pp 2379—2396

Dysregulation of FOXD2-AS1 promotes cell proliferation and migration and predicts poor prognosis in oral squamous cell carcinoma: a study based on TCGA data

Differentially expressed genes (DEGs) in High FOXD2-AS1 expression and Low FOXD2-AS1 expression samples and functional cluster analysis. (A) Heat map of top 5 DEGs in high and low FOXD2-AS1 expression groups. (B) Volcano map of DEGs with |log2FoldChange >2| and adjusted P valueC–F) Significantly enriched GO and KEGG annotations of FOXD2-AS1 related genes. (G, H) Enrichment of genes in E2F targets and G2/M checkpoint by GSEA.

Figure 5. Differentially expressed genes (DEGs) in High FOXD2-AS1 expression and Low FOXD2-AS1 expression samples and functional cluster analysis. (A) Heat map of top 5 DEGs in high and low FOXD2-AS1 expression groups. (B) Volcano map of DEGs with |log2FoldChange >2| and adjusted P value<0.05. (CF) Significantly enriched GO and KEGG annotations of FOXD2-AS1 related genes. (G, H) Enrichment of genes in E2F targets and G2/M checkpoint by GSEA.