**Figure 4.** **Construction of risk score model based on prognostic RBPs in the TCGA-LIHC cohort.** (**A**) Each curve represents an RBP, and the best lambda was calculated to minimize mean cross-validated error. (**B**) Cross-validation for tuning parameter selection in the proportional hazards model. (**C**) Kaplan–Meier survival curve of TCGA-LIHC patients. (**D**) Time-dependent ROC curves for predicting OS based on risk scores. (**E**) TCGA-LIHC patients were divided into low-risk group and high-risk group by the median of risk score values. (**F**) Scatter plots show that different risk scores indicate different survival outcomes in the TCGA-LIHC patients. (**G**) The heatmap exhibited the 11 RBPs expression profiles in each TCGA-LIHC patient. Red was defined as high expression and blue indicated as low expression.