Research Paper Advance Articles

A novel Foxp3-related immune prognostic signature for glioblastoma multiforme based on immunogenomic profiling

Construction of the Foxp3-related immune prognostic signature (IPS). (A–C) LASSO Cox analysis identified four genes most correlated with overall survival in the training set (n=76). (D, G) Kaplan–Meier curves of overall survival based on the IPS in the training set and validation set (n=76). (E, H) ROC curve analysis of the IPS. (F, I) Risk scores distribution, survival status of each patient, and heatmaps of prognostic four-gene signature in the training set (n=76) and validation set (n=76).

Figure 4. Construction of the Foxp3-related immune prognostic signature (IPS). (AC) LASSO Cox analysis identified four genes most correlated with overall survival in the training set (n=76). (D, G) Kaplan–Meier curves of overall survival based on the IPS in the training set and validation set (n=76). (E, H) ROC curve analysis of the IPS. (F, I) Risk scores distribution, survival status of each patient, and heatmaps of prognostic four-gene signature in the training set (n=76) and validation set (n=76).