Research Paper Volume 13, Issue 2 pp 2593—2603

Antitumor effect of poly lactic acid nanoparticles loaded with cisplatin and chloroquine on the oral squamous cell carcinoma

CDDP/CQ-PLA NPs induces caspase-dependent apoptosis. (A) Cell apoptosis in CAL-27 using Annexin-V/PI assay; (B) Western blot of Bax, Bid, Bim, Bcl-2, Caspase-3, and Caspase-9, β-actin as reference. *P

Figure 3. CDDP/CQ-PLA NPs induces caspase-dependent apoptosis. (A) Cell apoptosis in CAL-27 using Annexin-V/PI assay; (B) Western blot of Bax, Bid, Bim, Bcl-2, Caspase-3, and Caspase-9, β-actin as reference. *P < 0.05, NC: PBS.