Research Paper Volume 13, Issue 2 pp 2700—2726

Identification of the ceRNA networks in α-MSH-induced melanogenesis of melanocytes

Differentially expressed lncRNAs, circRNAs, and mRNAs in α-MSH-treated melanocytes. (A) qRT-PCR was used to detect the expression of melanogenesis related genes (MITF, TYR, TYRP1, DCT, RAB27A, and MYO5A) in α-MSH-induced melanocytes. (B–D) Scatter plot of normalized expression levels for differentially expressed lncRNAs, circRNAs, and mRNAs, respectively. Red dots: upregulated lncRNAs, circRNAs, and mRNAs; Blue dots : downregulated lncRNAs, circRNAs, and mRNAs.

Figure 1. Differentially expressed lncRNAs, circRNAs, and mRNAs in α-MSH-treated melanocytes. (A) qRT-PCR was used to detect the expression of melanogenesis related genes (MITF, TYR, TYRP1, DCT, RAB27A, and MYO5A) in α-MSH-induced melanocytes. (BD) Scatter plot of normalized expression levels for differentially expressed lncRNAs, circRNAs, and mRNAs, respectively. Red dots: upregulated lncRNAs, circRNAs, and mRNAs; Blue dots : downregulated lncRNAs, circRNAs, and mRNAs.