Research Paper Volume 13, Issue 2 pp 2727—2749

Melatonin protects against oxybenzone-induced deterioration of mouse oocytes during maturation

Effects of melatonin on body weight, ovary weight, the rate of PBE, the concentration of OBZ, and embryo development from OBZ-exposed mice in vivo. All parameters were measured throughout the experimental period (6–10 weeks). (A–F) Body weight (A), ovary weight (B), extrusion rate of PB1 (C), concentrations of OBZ (D), and embryo development rate (E, F) from the 2-cell stage to blastocyst stage in each treatment group. Values indicated by different letters are significantly different (P

Figure 7. Effects of melatonin on body weight, ovary weight, the rate of PBE, the concentration of OBZ, and embryo development from OBZ-exposed mice in vivo. All parameters were measured throughout the experimental period (6–10 weeks). (AF) Body weight (A), ovary weight (B), extrusion rate of PB1 (C), concentrations of OBZ (D), and embryo development rate (E, F) from the 2-cell stage to blastocyst stage in each treatment group. Values indicated by different letters are significantly different (P < 0.05). Control, untreated control group; OBZ, oxybenzone-exposed group; OBZ+MT, “oxybenzone + melatonin” treatment group.