Research Paper Volume 13, Issue 2 pp 2851—2863

A novel methylation signature predicts inferior outcome of patients with PDAC

LASSO regression analysis to construct PDAC specific diagnosis model. (A) Least absolute shrinkage and selection operator (LASSO) coefficient profiles of differential methylation site. (B) Cross-validation for tuning parameter selection in the LASSO model, the two dotted vertical lines are drawn at the optimal values by lambda. min 0.06973033 and lambda.1se 0.2032676.

Figure 1. LASSO regression analysis to construct PDAC specific diagnosis model. (A) Least absolute shrinkage and selection operator (LASSO) coefficient profiles of differential methylation site. (B) Cross-validation for tuning parameter selection in the LASSO model, the two dotted vertical lines are drawn at the optimal values by lambda. min 0.06973033 and lambda.1se 0.2032676.