Research Paper Volume 13, Issue 2 pp 2885—2894

Serum response factor, a novel early diagnostic biomarker of acute kidney injury

The ROC curve of renal SRF mRNA, renal SRF protein, urinary SRF, serum SRF and Scr in early (before 24 h) AKI. (A–E) The measured values (SRF mRNA, SRF protein, urinary SRF, serum SRF and Scr) of the AKI group (all time points after AKI as one group) were compared to those of the control group. The cutoff thresholds represent the fold change in measured values in the AKI group compared with the control group.

Figure 5. The ROC curve of renal SRF mRNA, renal SRF protein, urinary SRF, serum SRF and Scr in early (before 24 h) AKI. (AE) The measured values (SRF mRNA, SRF protein, urinary SRF, serum SRF and Scr) of the AKI group (all time points after AKI as one group) were compared to those of the control group. The cutoff thresholds represent the fold change in measured values in the AKI group compared with the control group.