Figure 4. Screening of differentially expressed RBPs based on PPI network. (A) PPI network of differentially expressed RBPs. (B) Gene module based on cytocubba. For A, red circles represent up-regulated RBPs and green circles for down-regulated RBPs. For B, the color layout varying from yellow to red indicates increasing significance of RBPs based on cytocubba. RBPs: RNA-binding proteins; PPI: protein-protein interaction.