Research Paper Volume 13, Issue 3 pp 4428—4451

Tsukushi is a novel prognostic biomarker and correlates with tumor-infiltrating B cells in non-small cell lung cancer

Correlations between differential TSKU methylation and expression in LUAD and LUSC. TCGA Infinium 450K methylation probes in the promoter region, including the cg20708175 and cg20886049 probes; (A–C) Scatterplots of correlations between differential TSKU methylation and expression level of all CpG sites (probes) in the promoter (A), cg20708175 (B), and cg20886049 (C) in LUAD (N = 471). (D–F) Scatterplots of correlations between differential TSKU methylation and expression level of all CpG sites (probes) in the promoter (D), cg20708175 (E), and cg20886049 (F) in LUSC (N = 406). Cor(r): the value determined by calculating the Pearson correlation coefficient.

Figure 5. Correlations between differential TSKU methylation and expression in LUAD and LUSC. TCGA Infinium 450K methylation probes in the promoter region, including the cg20708175 and cg20886049 probes; (AC) Scatterplots of correlations between differential TSKU methylation and expression level of all CpG sites (probes) in the promoter (A), cg20708175 (B), and cg20886049 (C) in LUAD (N = 471). (DF) Scatterplots of correlations between differential TSKU methylation and expression level of all CpG sites (probes) in the promoter (D), cg20708175 (E), and cg20886049 (F) in LUSC (N = 406). Cor(r): the value determined by calculating the Pearson correlation coefficient.