Research Paper Volume 13, Issue 2 pp 3031—3044

Triptolide improves neurobehavioral functions, inflammation, and oxidative stress in rats under deep hypothermic circulatory arrest

TPL increased brain neurotrophins in DHCA rats. On day 7 post operation, rats were euthanized and collected brain tissues to measure brain neurotrophins levels. The levels of brain BDNF (A), NGF (B), NT-3 (C) and NT-4 (D) were increased with TPL treatment after DHCA. Values were presented as x¯±s (n = 10). A difference with P

Figure 4. TPL increased brain neurotrophins in DHCA rats. On day 7 post operation, rats were euthanized and collected brain tissues to measure brain neurotrophins levels. The levels of brain BDNF (A), NGF (B), NT-3 (C) and NT-4 (D) were increased with TPL treatment after DHCA. Values were presented as x¯±s (n = 10). A difference with P < 0.05 was indicated statically significant. One-way ANOVA followed by Bonferroni's multiple comparison tests was performed to analyze differences between groups.