Review Volume 13, Issue 1 pp 1528—1564

Function of Deptor and its roles in hematological malignancies

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Figure 8.

Deptor expression in Acute Lymphocytic Leukemia. Oncomine analysis of Deptor expression in ALL was revised. (A) in Coustan Smith et al, expression analysis shows a higher expression in T-ALL vs normal cells and B-ALL (*p=0.05). (B) analysis of minimal residual disease in relationship with Deptor expression, we observed moderate high Deptor expression in patients with positive MRD (*p>0.05). (C) Another study presents by Bhojwani et al, a significant higher Deptor expression was observed in T-ALL compared to B-ALL (*p<0.001), (D) In the same study the Deptor expression was related to recurrence of the disease compared with primary recurrence. Moderate high Deptor expression was related with recurrence (*p<0.05). (E) On the other study presented by Andersson et al, Deptor expression is low in B-ALL compared with Bone Marrow (*p= N/S). (F) On Haferlach et al. study, very low Deptor expression in B-ALL and in B-ALL childhood were observed compared with PBMC (*p= N/S).