Research Paper Volume 13, Issue 4 pp 5674—5685

High expression of heme oxygenase-1 in tumor-associated macrophages characterizes a poor-prognosis subtype in nasopharyngeal carcinoma

HO-1 is a superior predictor for survival compared with CD163 in the studied cohort. The predictive capability of HO-1 and CD163 for survival is accessed by the area under the curve (AUC) of the receiver operating characteristic (ROC) curves. (A) HO-1 exhibits a superior ability in predicting overall survival compared with CD163. (B) HO-1 exhibits a superior ability in predicting progression-free survival compared with CD163. (C) The AUC values of HO-1 in predicting OS and PFS of patients were 0.707 and 0.685, which are slightly higher than those of CD163 (0.667 and 0.620).

Figure 5. HO-1 is a superior predictor for survival compared with CD163 in the studied cohort. The predictive capability of HO-1 and CD163 for survival is accessed by the area under the curve (AUC) of the receiver operating characteristic (ROC) curves. (A) HO-1 exhibits a superior ability in predicting overall survival compared with CD163. (B) HO-1 exhibits a superior ability in predicting progression-free survival compared with CD163. (C) The AUC values of HO-1 in predicting OS and PFS of patients were 0.707 and 0.685, which are slightly higher than those of CD163 (0.667 and 0.620).