Research Paper Volume 13, Issue 2 pp 3112—3145

Identification of core genes for early diagnosis and the EMT modulation of ovarian serous cancer by bioinformatics perspective

Correlation analysis of the core genes and EMT regulators in datasets (A) GES36668, (B) GES54388, (C) GSE69428. (D) The PPIs network of core genes and EMT regulators. The red color indicates core genes, and the green color predicts EMT regulators. (E) KEGG pathway enrichment analysis of core genes and EMT regulators. Only the enriched pathways with FDRF) The ovary-specific PPIs integrated network of core genes and EMT regulators, the red color indicates core genes, the green color predicts EMT regulators and the purple color represents transcription factors. (G) An overview of the alteration of the core genes and EMT regulators in the genomics datasets of OSC in the TCGA database.

Figure 6. Correlation analysis of the core genes and EMT regulators in datasets (A) GES36668, (B) GES54388, (C) GSE69428. (D) The PPIs network of core genes and EMT regulators. The red color indicates core genes, and the green color predicts EMT regulators. (E) KEGG pathway enrichment analysis of core genes and EMT regulators. Only the enriched pathways with FDR<0.05 were presented. The green lines represent percentage of count in gene set and the red lines represent -Log10 (FDR). (F) The ovary-specific PPIs integrated network of core genes and EMT regulators, the red color indicates core genes, the green color predicts EMT regulators and the purple color represents transcription factors. (G) An overview of the alteration of the core genes and EMT regulators in the genomics datasets of OSC in the TCGA database.