Research Paper Volume 13, Issue 2 pp 1742—1764

DNA methylation perturbations may link altered development and aging in the lung

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Figure 1.

Manhattan plot depicting significance on y-axis and distribution of CpGs across all chromosomes on x-axis for fetal lung dataset (top panel) and adult lung dataset associations with age (bottom panel). Top 20 CpGs in both datasets have been highlighted in green. The two red lines represent the CpG sites significant at an FDR<0.05 and at a Bonferroni threshold (0.05/number of tests) in fetal and adult lung datasets.