Research Paper Volume 13, Issue 5 pp 7259—7283

Pan-cancer investigation reveals mechanistic insights of planar cell polarity gene Fuz in carcinogenesis

Coding sequence alterations in Fuz were identified across multiple cancer types. (A) cBioportal online database was used to investigate Fuz coding sequence alterations in multiples types of cancer. (B) A relative higher mutation frequency was identified at the 404th arginine residue within the coding sequence at Fuz locus. (C) The missense and nonsense mutations at FuzR404 were identified in 4 patient samples from 3 independent studies.

Figure 7. Coding sequence alterations in Fuz were identified across multiple cancer types. (A) cBioportal online database was used to investigate Fuz coding sequence alterations in multiples types of cancer. (B) A relative higher mutation frequency was identified at the 404th arginine residue within the coding sequence at Fuz locus. (C) The missense and nonsense mutations at FuzR404 were identified in 4 patient samples from 3 independent studies.