Figure 3. SMCs specific SETD2 deficient ameliorates right ventricular function in a hypoxia-induced mouse model of PAH. Echocardiography was used to measure the normalized cardiac cycle length measuring pulmonary acceleration time (PAAT/CL), RV end diastolic dimension (RVEDD), RV diastolic contraction size (RVESD), RV end diastolic volume (RVEDV), RV diastolic volume contraction (RVESV), RV cardiac output (RVCO), RV wall thickness (RVWT), the thickness of interventricular septum (IVS), RV ejection fraction (RVEF) and RV shortening fraction (RVFS). All data were presented as Mean±SD (n=5). *P<0.05, **P<0.01 vs. corresponding group.