Research Paper Volume 13, Issue 7 pp 9627—9645

Hsa_circ_0053063 inhibits breast cancer cell proliferation via hsa_circ_0053063/hsa-miR-330-3p/PDCD4 axis

MiR-330-3p highly expresses and acts as an oncogene in BC cells. (A–B) QRT-PCR assays revealed miR-330-3p expression in BC patient tissues and BC cell lines. (C–H) MTT assays and colony formation assays were performed in MDA-MB-231 and MDA-MB-468 cell lines to determine the effect of miR-330-3p-inhibitor and miR-330-3p-mimics on proliferation. (I–J) Effect of miR-330-3p-mimics on proliferation in MDA-MB-231 and MDa-MB-468 cells by western blot. (*p **p ***p ****p

Figure 5. MiR-330-3p highly expresses and acts as an oncogene in BC cells. (A–B) QRT-PCR assays revealed miR-330-3p expression in BC patient tissues and BC cell lines. (C–H) MTT assays and colony formation assays were performed in MDA-MB-231 and MDA-MB-468 cell lines to determine the effect of miR-330-3p-inhibitor and miR-330-3p-mimics on proliferation. (I–J) Effect of miR-330-3p-mimics on proliferation in MDA-MB-231 and MDa-MB-468 cells by western blot. (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).