Research Paper Volume 13, Issue 7 pp 10659—10671

Anti-inflammatory effect of resveratrol attenuates the severity of diabetic neuropathy by activating the Nrf2 pathway

(A, B) Western blot analysis of lysates of p-p65/p65, MCP-1, TNF-a, IL-1β from STZ+Vehicle and STZ+Resveratrol mice, Quantification by Western blot analysis showed that the activation of AKT and the Bax, Cleaved caspase3 decreased in STZ+Resveratrol mice at 12 weeks after STZ injection (n = 3 nerves for each group, data are represented as the mean ± SEM.).

Figure 5. (A, B) Western blot analysis of lysates of p-p65/p65, MCP-1, TNF-a, IL-1β from STZ+Vehicle and STZ+Resveratrol mice, Quantification by Western blot analysis showed that the activation of AKT and the Bax, Cleaved caspase3 decreased in STZ+Resveratrol mice at 12 weeks after STZ injection (n = 3 nerves for each group, data are represented as the mean ± SEM.).