Figure 5. The relationship between changed microbiotas and altered metabolites. (A) Correlation square heatmap, (B) circular heatmap, and (C) the network of associations between the differential OTUs of gut microbes and the differentially expressed metabolites. Red color indicates a positive correlation and the blue color represents a negative correlation. A deeper color indicates a greater degree of correlation (*P < 0.05 and **P < 0.01).