Research Paper Volume 13, Issue 8 pp 11833—11859

Transcriptome integration analysis and specific diagnosis model construction for Hodgkin's lymphoma, diffuse large B-cell lymphoma, and mantle cell lymphoma

Expression and functional interaction network of lymphoma marker genes. (A) Log2 transformed the fold-change (logFC) of lymphoma marker genes in different comparisons. The orange color indicates the logFC of the gene > 0, and the cyan color indicates the logFC of the gene B) Functional interaction network of HL marker genes. (C) Functional interaction network of DLBCL marker genes. No records of CCDC144B or PRO2964 were found in the GeneMANIA database. (D) Functional interaction network of MCL marker genes. No records of IGLV3-19, IGKV4-1, or IGLV4-60 were found in the GeneMANIA database. (E) Enriched functions of HL marker genes and query genes. (F) Enriched functions of DLBCL marker genes and query genes. (G) Enriched functions of MCL marker genes and query genes. HL, Hodgkin's lymphoma; DLBCL, diffuse large B-cell lymphoma; MCL, mantle cell lymphoma.

Figure 2. Expression and functional interaction network of lymphoma marker genes. (A) Log2 transformed the fold-change (logFC) of lymphoma marker genes in different comparisons. The orange color indicates the logFC of the gene > 0, and the cyan color indicates the logFC of the gene < 0. (B) Functional interaction network of HL marker genes. (C) Functional interaction network of DLBCL marker genes. No records of CCDC144B or PRO2964 were found in the GeneMANIA database. (D) Functional interaction network of MCL marker genes. No records of IGLV3-19, IGKV4-1, or IGLV4-60 were found in the GeneMANIA database. (E) Enriched functions of HL marker genes and query genes. (F) Enriched functions of DLBCL marker genes and query genes. (G) Enriched functions of MCL marker genes and query genes. HL, Hodgkin's lymphoma; DLBCL, diffuse large B-cell lymphoma; MCL, mantle cell lymphoma.