Research Paper Volume 13, Issue 8 pp 12058—12066

Circ_0007841 accelerates ovarian cancer development through facilitating MEX3C expression by restraining miR-151-3p activity

miR-151-3p targets MEX3C. (A) MEX3C was predicted to be the target of miR-151-3p via TargetSan, miRDB and starBase. (B) Luciferase reporter assay. (C) RIP assay was performed to validate the interaction between miR-151-3p and MEX3C. (D) Relative expression of MEX3C was analyzed by qRT-PCR. (E) Expression correlation between MEX3C and miR-151-3p in OC tissues. (F) Expression correlation between MEX3C and circ

Figure 5. miR-151-3p targets MEX3C. (A) MEX3C was predicted to be the target of miR-151-3p via TargetSan, miRDB and starBase. (B) Luciferase reporter assay. (C) RIP assay was performed to validate the interaction between miR-151-3p and MEX3C. (D) Relative expression of MEX3C was analyzed by qRT-PCR. (E) Expression correlation between MEX3C and miR-151-3p in OC tissues. (F) Expression correlation between MEX3C and circ_0007841 in OC tissues. (G) Relative expression of MEX3C was analyzed by qRT-PCR after transfection. *P<0.05 by Student’s t-test.