Research Paper Volume 13, Issue 16 pp 20094—20115

Overexpressed DEPDC1B contributes to the progression of hepatocellular carcinoma by CDK1

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Figure 4.

Potential mechanisms of DEPDC1B functions on HCC. (AC) Bcl-2, Bcl-w, HSP27, HSP70, Livin, sTNF-R2, TNF-α, and TNF-β was significantly down-regulated in shDEPDC1B (P<0.05). (D) P-Akt, CDK6, Cyclin D1, and PIK3CA was down-regulated in shDEPDC1B group.