Research Paper Volume 13, Issue 12 pp 16088—16104

High glucose exacerbates neuroinflammation and apoptosis at the intermediate stage after post-traumatic brain injury

Hyperglycemia exacerbated neurological dysfunction and cognitive deficits due to TBI. (A) mNSS. (B) Rotating rod test. (C) Forelimb placement test. (D–G) MWM test. All data are presented as the mean ± standard error (n = 8 per group). Statistical significance was determined using one-way ANOVA followed by post-hoc Bonferroni correction. #P ##P *P **P

Figure 1. Hyperglycemia exacerbated neurological dysfunction and cognitive deficits due to TBI. (A) mNSS. (B) Rotating rod test. (C) Forelimb placement test. (DG) MWM test. All data are presented as the mean ± standard error (n = 8 per group). Statistical significance was determined using one-way ANOVA followed by post-hoc Bonferroni correction. #P < 0.05 or ##P < 0.01 vs. the Sham group; *P < 0.05 or **P < 0.01 vs. the TBI group.