Research Paper Volume 13, Issue 12 pp 16198—16218

A risk signature of four aging-related genes has clinical prognostic value and is associated with a tumor immune microenvironment in glioma

Association of six types of immune cells with the risk score and four selected AGs in the TCGA datasets. (A) Distributions of the six types of immune cells (naïve B cells, plasma cells, CD4 memory resting T cells, NK activated cells, monocytes, and M0 macrophages) in the two subtypes grouped by the median risk score. (B–E) Comparison of the six types of immune cells (naïve B cells, plasma cells, CD4 memory resting T cells, NK activated cells, monocytes, and M0 macrophages) according to LEP (B), TERT (C), PON1 (D), and SSTR3 (E) expression levels. Non-significant (ns) P > 0.05, * P P P

Figure 7. Association of six types of immune cells with the risk score and four selected AGs in the TCGA datasets. (A) Distributions of the six types of immune cells (naïve B cells, plasma cells, CD4 memory resting T cells, NK activated cells, monocytes, and M0 macrophages) in the two subtypes grouped by the median risk score. (BE) Comparison of the six types of immune cells (naïve B cells, plasma cells, CD4 memory resting T cells, NK activated cells, monocytes, and M0 macrophages) according to LEP (B), TERT (C), PON1 (D), and SSTR3 (E) expression levels. Non-significant (ns) P > 0.05, * P < 0.05, ** P < 0.01, and *** P < 0.001.