Research Paper Volume 13, Issue 11 pp 14829—14842

Effect of samul-tang on female fertility via RAS signaling pathway in ovaries of aged mice

Histological analysis of ovarian follicles in mice after Samul-tang (SM) administration. (A) Eight-week-old mice were orally administered distilled water (n = 6, YC group). Forty-week-old mice were orally administered distilled water (n = 6, OC group) or 2.5 g/kg of SM (n = 7, OC+SM group) five times a week for four weeks. (B) Post SM administration, both mouse ovaries were assessed histologically. (C) Number of ovarian follicles in different stages and the total number of ovarian follicles. Data are presented as mean ± standard error of the mean. Statistical analysis was performed using the Student’s t-test.

Figure 2. Histological analysis of ovarian follicles in mice after Samul-tang (SM) administration. (A) Eight-week-old mice were orally administered distilled water (n = 6, YC group). Forty-week-old mice were orally administered distilled water (n = 6, OC group) or 2.5 g/kg of SM (n = 7, OC+SM group) five times a week for four weeks. (B) Post SM administration, both mouse ovaries were assessed histologically. (C) Number of ovarian follicles in different stages and the total number of ovarian follicles. Data are presented as mean ± standard error of the mean. Statistical analysis was performed using the Student’s t-test.