Research Paper Volume 13, Issue 11 pp 14829—14842

Effect of samul-tang on female fertility via RAS signaling pathway in ovaries of aged mice


Figure 8. In vivo implantation potential after Samul-tang (SM) administration. Forty-week-old mice were orally administered distilled water (n = 20, OC group) or 2.5 g/kg of SM (n = 10, OC+SM group) five times a week for four weeks. Post SM administration, the mice were superovulated via hormonal stimulation and mated with fertile males. (A) At 9.5 days post coitum (dpc), the uterus from mice of both the groups was collected to assess the implantation potential. (B) Pregnancy rates. (C) Number of litters. (D) Weight of litters. Data are presented as mean ± standard error of the mean. Statistical analysis was performed using the Student’s t-test. The significance of difference in pregnancy rates was determined using Fisher’s exact test.