Research Paper Volume 13, Issue 12 pp 16219—16228

Immunological discrepancy in aged mice facilitates skin allograft survival

A representative of induced regulatory T-cells. Enriched T-cells derived from aged and young B10 mice were activated by C3H DC for 3 days, a higher frequency of CD4+foxp3+ regulatory cells was induced in the T-cells derived from aged mice (B) than young mice (A) (7.87 ± 3.42% versus 5.04 ± 2.71%, p = 0.023).

Figure 4. A representative of induced regulatory T-cells. Enriched T-cells derived from aged and young B10 mice were activated by C3H DC for 3 days, a higher frequency of CD4+foxp3+ regulatory cells was induced in the T-cells derived from aged mice (B) than young mice (A) (7.87 ± 3.42% versus 5.04 ± 2.71%, p = 0.023).