Research Paper Volume 13, Issue 12 pp 16229—16247

Testosterone ameliorates age-related brain mitochondrial dysfunction

TP supplementation preserves neuronal integrity in the HIPP of aged male rats. (A–C) Representative photomicrographs of hippocampal sections stained with HE. Scale bars = 200 μm (upper panel), 20 μm (lower panel). (D) Quantification of karyopyknosis in the CA1 pyramidal stratum of the HIPP. Data are expressed as the mean ± S.D. (n = 6/group). #P U test, Bonferroni correction).

Figure 4. TP supplementation preserves neuronal integrity in the HIPP of aged male rats. (AC) Representative photomicrographs of hippocampal sections stained with HE. Scale bars = 200 μm (upper panel), 20 μm (lower panel). (D) Quantification of karyopyknosis in the CA1 pyramidal stratum of the HIPP. Data are expressed as the mean ± S.D. (n = 6/group). #P < 0.0167 (Mann-Whitney U test, Bonferroni correction).