Research Paper Volume 13, Issue 12 pp 16287—16315

Immune infiltration-related N6-methyladenosine RNA methylation regulators influence the malignancy and prognosis of endometrial cancer

Relationship between copy number variants of m6A regulatory genes and OS/DFS in 412 EC patients (A-i) OS of EC patients with or without mutations in m6A regulatory genes. (A-ii) OS of EC patients with different CNV types for IGF2BP1, ZC3H13, METTL14, ALKBH5, and YTHDC1. (B-i) DFS of EC patients with or without mutations in m6A regulatory genes. (B-ii) DFS of EC patients with different CNV types for IGF2BP1, ZC3H13, METTL14, ALKBH5, and YTHDC1. (C) OS and DFS of EC patients with simultaneous alterations in writer and eraser genes.

Figure 2. Relationship between copy number variants of m6A regulatory genes and OS/DFS in 412 EC patients (A-i) OS of EC patients with or without mutations in m6A regulatory genes. (A-ii) OS of EC patients with different CNV types for IGF2BP1, ZC3H13, METTL14, ALKBH5, and YTHDC1. (B-i) DFS of EC patients with or without mutations in m6A regulatory genes. (B-ii) DFS of EC patients with different CNV types for IGF2BP1, ZC3H13, METTL14, ALKBH5, and YTHDC1. (C) OS and DFS of EC patients with simultaneous alterations in writer and eraser genes.