Research Paper Volume 13, Issue 12 pp 16367—16380

High S100A9+ cell density predicts a poor prognosis in hepatocellular carcinoma patients after curative resection

Prognostic value of S100A9+ cell in HCC patients. A high S100A9+ cell density in nontumor or tumor tissue was associated with poor OS (A, C) and a high recurrence rate (B, D) in HCC patients. Forest plots showing the association between S100A9 expression in tumors and clinicopathological features in HCC patients using univariate (E) or multivariate analysis (F). Patients were divided into two groups according to the median value of the S100A9+ cell density in nontumoral and tumoral tissues. The cumulative OS (G) and recurrence (H) times were calculated using the Kaplan-Meier method and then analyzed with the log-rank test.

Figure 3. Prognostic value of S100A9+ cell in HCC patients. A high S100A9+ cell density in nontumor or tumor tissue was associated with poor OS (A, C) and a high recurrence rate (B, D) in HCC patients. Forest plots showing the association between S100A9 expression in tumors and clinicopathological features in HCC patients using univariate (E) or multivariate analysis (F). Patients were divided into two groups according to the median value of the S100A9+ cell density in nontumoral and tumoral tissues. The cumulative OS (G) and recurrence (H) times were calculated using the Kaplan-Meier method and then analyzed with the log-rank test.