Research Paper Volume 13, Issue 12 pp 16445—16470

Identification and validation of inferior prognostic genes associated with immune signatures and chemotherapy outcome in acute myeloid leukemia

The module driver genes identified in the PPI network. (A) The PPI network consists of 45 nodes and 66 edges, and 75 of the Blue module's co-expression of genes constructs a PPI network; (B) Clusters of driver genes in the Blue module, and the squares marked in yellow to red indicate the top 10 module driver genes in sub-function cluster 1, and the blue squares represented the other related genes in cluster 1. Abbreviation: PPI: protein-protein interaction.

Figure 5. The module driver genes identified in the PPI network. (A) The PPI network consists of 45 nodes and 66 edges, and 75 of the Blue module's co-expression of genes constructs a PPI network; (B) Clusters of driver genes in the Blue module, and the squares marked in yellow to red indicate the top 10 module driver genes in sub-function cluster 1, and the blue squares represented the other related genes in cluster 1. Abbreviation: PPI: protein-protein interaction.