Research Paper Volume 13, Issue 12 pp 16667—16683

Correlation of IL-6 and JAK2/STAT3 signaling pathway with prognosis of nasopharyngeal carcinoma patients

The protein expressions of IL-6, STAT3, JAK2, and CyclinD1 as well as the extent of STAT3 and JAK2 phosphorylation in NPC tissues were higher. (A) The protein band detected by western blot analysis; (B) Densitometry analysis of Western blot data. *p n = 117); Normal nasopharyngeal epithelial tissues (n = 112). Abbreviation: NPC: nasopharyngeal carcinoma.

Figure 3. The protein expressions of IL-6, STAT3, JAK2, and CyclinD1 as well as the extent of STAT3 and JAK2 phosphorylation in NPC tissues were higher. (A) The protein band detected by western blot analysis; (B) Densitometry analysis of Western blot data. *p < 0.05 when vs. normal nasopharyngeal epithelial tissues; NPC tissues (n = 117); Normal nasopharyngeal epithelial tissues (n = 112). Abbreviation: NPC: nasopharyngeal carcinoma.