Research Paper Volume 13, Issue 12 pp 16667—16683

Correlation of IL-6 and JAK2/STAT3 signaling pathway with prognosis of nasopharyngeal carcinoma patients

Upregulated IL-6, SATA3, p-SATA3, JAK2, p-JAK2, CyclinD1 expression was associated with decreased survival time in NPC patients. (A) Kaplan-Meier survival curve of the overall survival of NPC patients; (B) Kaplan-Meier survival curve of correlation between IL-6 expression and the survival time of patients; (C) Kaplan-Meier survival curve of correlation between STAT3 expression and the survival time of patients; (D) Kaplan-Meier survival curve of correlation between p-STAT3 expression and the survival time of patients; (E) Kaplan-Meier survival curve of correlation between JAK2 expression and the survival time of patients; (F) Kaplan-Meier survival curve of correlation between p-JAK2 expression and the survival time of patients; (G) Kaplan-Meier survival curve of correction between CyclinD1 expression and the survival time of patients.

Figure 4. Upregulated IL-6, SATA3, p-SATA3, JAK2, p-JAK2, CyclinD1 expression was associated with decreased survival time in NPC patients. (A) Kaplan-Meier survival curve of the overall survival of NPC patients; (B) Kaplan-Meier survival curve of correlation between IL-6 expression and the survival time of patients; (C) Kaplan-Meier survival curve of correlation between STAT3 expression and the survival time of patients; (D) Kaplan-Meier survival curve of correlation between p-STAT3 expression and the survival time of patients; (E) Kaplan-Meier survival curve of correlation between JAK2 expression and the survival time of patients; (F) Kaplan-Meier survival curve of correlation between p-JAK2 expression and the survival time of patients; (G) Kaplan-Meier survival curve of correction between CyclinD1 expression and the survival time of patients.