Research Paper Volume 13, Issue 13 pp 17227—17236

miR-let-7c-5p and miR-149-5p inhibit proinflammatory cytokine production in osteoarthritis and rheumatoid arthritis synovial fibroblasts

Higher levels of proinflammatory cytokines in OA and RA synovial fibroblasts. Levels of IL-1β, IL-6 and TNF-α protein (A–C) and mRNA expression (D–F) in NSFs, OASFs and RASFs were examined by Western blot and qPCR assays.

Figure 1. Higher levels of proinflammatory cytokines in OA and RA synovial fibroblasts. Levels of IL-1β, IL-6 and TNF-α protein (AC) and mRNA expression (DF) in NSFs, OASFs and RASFs were examined by Western blot and qPCR assays.