Research Paper Volume 13, Issue 12 pp 15815—15832

Spatiotemporal dynamics of γH2AX in the mouse brain after acute irradiation at different postnatal days with special reference to the dentate gyrus of the hippocampus

γH2AX immunostaining counterstained with hematoxylin shows irradiation-induced γH2AX foci (arrows) in different brain regions including cortex (A), stratum granulosum of the dentate gyrus (B), stratum pyramidale of CA1 area of the hippocampus (C), corpus callosum (CC) (D), striatum (E), thalamus (F), olfactory bulb (G) and subventricular zone of the lateral ventricle (H) at 120 days after irradiation at P3. Scan bar=50μm in (A) applies to (B–H).

Figure 6. γH2AX immunostaining counterstained with hematoxylin shows irradiation-induced γH2AX foci (arrows) in different brain regions including cortex (A), stratum granulosum of the dentate gyrus (B), stratum pyramidale of CA1 area of the hippocampus (C), corpus callosum (CC) (D), striatum (E), thalamus (F), olfactory bulb (G) and subventricular zone of the lateral ventricle (H) at 120 days after irradiation at P3. Scan bar=50μm in (A) applies to (BH).